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ARID1A regulates R-loop associated DNA replication stress

ARID1A is a core DNA-binding subunit of the BAF chromatin remodeling complex, and is lost in up to 7% of all cancers. The frequency of ARID1A loss increases in certain cancer types, such as clear cell ovarian carcinoma where ARID1A protein is lost in about 50% of cases. While the impact of ARID1A lo...

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Detalles Bibliográficos
Autores principales:	Tsai, Shuhe, Fournier, Louis-Alexandre, Chang, Emily Yun-chia, Wells, James P., Minaker, Sean W., Zhu, Yi Dan, Wang, Alan Ying-Hsu, Wang, Yemin, Huntsman, David G., Stirling, Peter C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055027/ https://www.ncbi.nlm.nih.gov/pubmed/33826602 http://dx.doi.org/10.1371/journal.pgen.1009238

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