Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer

Evaluating the structure-function relationship of viral envelope (Env) evolution and the development of broadly cross-neutralizing antibodies (bnAbs) in natural infection can inform rational immunogen design. In the present study, we examined the magnitude and specificity of autologous neutralizing...

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Detalles Bibliográficos
Autores principales: Kumar, Rajesh, Deshpande, Suprit, Sewall, Leigh M., Ozorowski, Gabriel, Cottrell, Christopher A., Lee, Wen-Hsin, Holden, Lauren G., Richey, Sara T., Chandrawacar, Antra Singh, Dhiman, Kanika, Ashish, Kumar, Vivek, Ahmed, Shubbir, Hingankar, Nitin, Kumar, Naresh, Murugavel, Kailapuri G., Srikrishnan, Aylur K., Sok, Devin, Ward, Andrew B., Bhattacharya, Jayanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055034/
https://www.ncbi.nlm.nih.gov/pubmed/33826683
http://dx.doi.org/10.1371/journal.ppat.1008977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055034/
https://www.ncbi.nlm.nih.gov/pubmed/33826683
http://dx.doi.org/10.1371/journal.ppat.1008977

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