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Sex-Specific Control of Human Heart Maturation by the Progesterone Receptor
BACKGROUND: Despite in-depth knowledge of the molecular mechanisms controlling embryonic heart development, little is known about the signals governing postnatal maturation of the human heart. METHODS: Single-nucleus RNA sequencing of 54 140 nuclei from 9 human donors was used to profile transcripti...
Autores principales: | Sim, Choon Boon, Phipson, Belinda, Ziemann, Mark, Rafehi, Haloom, Mills, Richard J., Watt, Kevin I., Abu-Bonsrah, Kwaku D., Kalathur, Ravi K.R., Voges, Holly K., Dinh, Doan T., ter Huurne, Menno, Vivien, Celine J., Kaspi, Antony, Kaipananickal, Harikrishnan, Hidalgo, Alejandro, Delbridge, Leanne M.D., Robker, Rebecca L., Gregorevic, Paul, dos Remedios, Cristobal G., Lal, Sean, Piers, Adam T., Konstantinov, Igor E., Elliott, David A., El-Osta, Assam, Oshlack, Alicia, Hudson, James E., Porrello, Enzo R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055196/ https://www.ncbi.nlm.nih.gov/pubmed/33682422 http://dx.doi.org/10.1161/CIRCULATIONAHA.120.051921 |
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