Cargando…

ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets

SUMMARY: The rapid progresses of high-throughput sequencing technology-based omics and mass spectrometry-based proteomics, such as data-independent acquisition and its penetration to clinical studies have generated increasing number of proteomic datasets containing hundreds to thousands of samples....

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Tiansheng, Chen, Hao, Yan, Xishan, Wu, Zhicheng, Zhou, Xiaoxu, Xiao, Qi, Ge, Weigang, Zhang, Qiushi, Xu, Chao, Xu, Luang, Ruan, Guan, Xue, Zhangzhi, Yuan, Chunhui, Chen, Guo-Bo, Guo, Tiannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055226/
https://www.ncbi.nlm.nih.gov/pubmed/33416829
http://dx.doi.org/10.1093/bioinformatics/btaa1088
_version_ 1783680412187361280
author Zhu, Tiansheng
Chen, Hao
Yan, Xishan
Wu, Zhicheng
Zhou, Xiaoxu
Xiao, Qi
Ge, Weigang
Zhang, Qiushi
Xu, Chao
Xu, Luang
Ruan, Guan
Xue, Zhangzhi
Yuan, Chunhui
Chen, Guo-Bo
Guo, Tiannan
author_facet Zhu, Tiansheng
Chen, Hao
Yan, Xishan
Wu, Zhicheng
Zhou, Xiaoxu
Xiao, Qi
Ge, Weigang
Zhang, Qiushi
Xu, Chao
Xu, Luang
Ruan, Guan
Xue, Zhangzhi
Yuan, Chunhui
Chen, Guo-Bo
Guo, Tiannan
author_sort Zhu, Tiansheng
collection PubMed
description SUMMARY: The rapid progresses of high-throughput sequencing technology-based omics and mass spectrometry-based proteomics, such as data-independent acquisition and its penetration to clinical studies have generated increasing number of proteomic datasets containing hundreds to thousands of samples. To analyze these quantitative proteomic datasets and other omics (e.g. transcriptomics and metabolomics) datasets more efficiently and conveniently, we present a web server-based software tool ProteomeExpert implemented in Docker, which offers various analysis tools for experimental design, data mining, interpretation and visualization of quantitative proteomic datasets. ProteomeExpert can be deployed on an operating system with Docker installed or with R language environment. AVAILABILITY AND IMPLEMENTATION: The Docker image of ProteomeExpert is freely available from https://hub.docker.com/r/lifeinfo/proteomeexpert. The source code of ProteomeExpert is also openly accessible at http://www.github.com/guomics-lab/ProteomeExpert/. In addition, a demo server is provided at https://proteomic.shinyapps.io/peserver/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
format Online
Article
Text
id pubmed-8055226
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-80552262021-04-28 ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets Zhu, Tiansheng Chen, Hao Yan, Xishan Wu, Zhicheng Zhou, Xiaoxu Xiao, Qi Ge, Weigang Zhang, Qiushi Xu, Chao Xu, Luang Ruan, Guan Xue, Zhangzhi Yuan, Chunhui Chen, Guo-Bo Guo, Tiannan Bioinformatics Applications Notes SUMMARY: The rapid progresses of high-throughput sequencing technology-based omics and mass spectrometry-based proteomics, such as data-independent acquisition and its penetration to clinical studies have generated increasing number of proteomic datasets containing hundreds to thousands of samples. To analyze these quantitative proteomic datasets and other omics (e.g. transcriptomics and metabolomics) datasets more efficiently and conveniently, we present a web server-based software tool ProteomeExpert implemented in Docker, which offers various analysis tools for experimental design, data mining, interpretation and visualization of quantitative proteomic datasets. ProteomeExpert can be deployed on an operating system with Docker installed or with R language environment. AVAILABILITY AND IMPLEMENTATION: The Docker image of ProteomeExpert is freely available from https://hub.docker.com/r/lifeinfo/proteomeexpert. The source code of ProteomeExpert is also openly accessible at http://www.github.com/guomics-lab/ProteomeExpert/. In addition, a demo server is provided at https://proteomic.shinyapps.io/peserver/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online. Oxford University Press 2021-01-08 /pmc/articles/PMC8055226/ /pubmed/33416829 http://dx.doi.org/10.1093/bioinformatics/btaa1088 Text en © The Author(s) 2021. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Applications Notes
Zhu, Tiansheng
Chen, Hao
Yan, Xishan
Wu, Zhicheng
Zhou, Xiaoxu
Xiao, Qi
Ge, Weigang
Zhang, Qiushi
Xu, Chao
Xu, Luang
Ruan, Guan
Xue, Zhangzhi
Yuan, Chunhui
Chen, Guo-Bo
Guo, Tiannan
ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets
title ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets
title_full ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets
title_fullStr ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets
title_full_unstemmed ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets
title_short ProteomeExpert: a Docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets
title_sort proteomeexpert: a docker image-based web server for exploring, modeling, visualizing and mining quantitative proteomic datasets
topic Applications Notes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055226/
https://www.ncbi.nlm.nih.gov/pubmed/33416829
http://dx.doi.org/10.1093/bioinformatics/btaa1088
work_keys_str_mv AT zhutiansheng proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT chenhao proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT yanxishan proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT wuzhicheng proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT zhouxiaoxu proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT xiaoqi proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT geweigang proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT zhangqiushi proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT xuchao proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT xuluang proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT ruanguan proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT xuezhangzhi proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT yuanchunhui proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT chenguobo proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets
AT guotiannan proteomeexpertadockerimagebasedwebserverforexploringmodelingvisualizingandminingquantitativeproteomicdatasets