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Development of ciclesonide analogues that block SARS-CoV-2 RNA replication

Ciclesonide is an inhaled corticosteroid used to treat asthma and is currently undergoing clinical trials for treatment of coronavirus disease 2019 (COVID-19). An active metabolite of ciclesonide, Cic2, was recently reported to repress severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) gen...

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Detalles Bibliográficos
Autores principales:	Tsuji, Genichiro, Yonemitsu, Kenzo, Ito, Takahito, Yanase, Yuta, Uema, Masashi, Ohoka, Nobumichi, Inoue, Takao, Asakura, Hiroshi, Demizu, Yosuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055493/ https://www.ncbi.nlm.nih.gov/pubmed/33887440 http://dx.doi.org/10.1016/j.bmcl.2021.128052

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