Spatially interacting phosphorylation sites and mutations in cancer

Advances in mass-spectrometry have generated increasingly large-scale proteomics datasets containing tens of thousands of phosphorylation sites (phosphosites) that require prioritization. We develop a bioinformatics tool called HotPho and systematically discover 3D co-clustering of phosphosites and...

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Detalles Bibliográficos
Autores principales: Huang, Kuan-lin, Scott, Adam D., Zhou, Daniel Cui, Wang, Liang-Bo, Weerasinghe, Amila, Elmas, Abdulkadir, Liu, Ruiyang, Wu, Yige, Wendl, Michael C., Wyczalkowski, Matthew A., Baral, Jessika, Sengupta, Sohini, Lai, Chin-Wen, Ruggles, Kelly, Payne, Samuel H., Raphael, Benjamin, Fenyö, David, Chen, Ken, Mills, Gordon, Ding, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055881/
https://www.ncbi.nlm.nih.gov/pubmed/33875650
http://dx.doi.org/10.1038/s41467-021-22481-w

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