Proteoglycans contribute to the functional integrity of the glomerular endothelial cell surface layer and are regulated in diabetic kidney disease

All capillary endothelia, including those of the glomeruli, have a luminal cell surface layer (ESL) consisting of glycoproteins, glycolipids, proteoglycans (PGs) and glycosaminoglycans. Previous results have demonstrated that an intact ESL is necessary for a normal filtration barrier and damage to t...

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Detalles Bibliográficos
Autores principales: Khramova, Alina, Boi, Roberto, Fridén, Vincent, Granqvist, Anna Björnson, Nilsson, Ulf, Tenstad, Olav, Oveland, Eystein, Haraldsson, Börje, Ebefors, Kerstin, Nyström, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055884/
https://www.ncbi.nlm.nih.gov/pubmed/33875683
http://dx.doi.org/10.1038/s41598-021-87753-3

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