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Eight-month follow-up of olfactory and gustatory dysfunctions in recovered COVID-19 patients

PURPOSE: To investigate the recovery of loss of smell and taste among recovered COVID-19 patients. MATERIALS AND METHODS: This cross-sectional follow-up study is a sequel to a study by Biadsee et al. Among the previous study population of 128 non-hospitalized patients, positive for COVID-19 by rever...

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Autores principales: Biadsee, Ameen, Dagan, Or, Ormianer, Zeev, Kassem, Firas, Masarwa, Shchada, Biadsee, Ameer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055924/
https://www.ncbi.nlm.nih.gov/pubmed/33894627
http://dx.doi.org/10.1016/j.amjoto.2021.103065
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author Biadsee, Ameen
Dagan, Or
Ormianer, Zeev
Kassem, Firas
Masarwa, Shchada
Biadsee, Ameer
author_facet Biadsee, Ameen
Dagan, Or
Ormianer, Zeev
Kassem, Firas
Masarwa, Shchada
Biadsee, Ameer
author_sort Biadsee, Ameen
collection PubMed
description PURPOSE: To investigate the recovery of loss of smell and taste among recovered COVID-19 patients. MATERIALS AND METHODS: This cross-sectional follow-up study is a sequel to a study by Biadsee et al. Among the previous study population of 128 non-hospitalized patients, positive for COVID-19 by reverse transcription-polymerase chain reaction (RT-PCR), 97 patients participated in a survey designed for this study. Information and data regarding loss of smell and taste, rate of recovery, xerostomia, and additional symptoms; (Cough, Myalgia, Weakness, Rhinorrhea, Nasal congestion) were collected. RESULTS: A total of 43 men and 54 women were included. Mean age was 37.5 years (range 19–74). Mean follow-up was 229 days (range 191–253). Sixty-five patients reported gustatory dysfunction during the disease of which 61.5% reported full recovery, 38.5% partial recovery. Of 65 patients who reported olfactory impairment during the disease, 52% had full recovery and 48% reported partial recovery of olfactory function. Complete recovery of olfactory function was positively associated with full recovery of gustatory function (p = 0.01). Gender did not significantly affect the recovery of OD and GD (p = 0.45, p = 0.90, respectively). Patients who experienced olfactory dysfunction as an initial symptom had lower rates of olfactory complete recovery (p = 0.043). CONCLUSION: After a mean follow-up of 229 days, complete recovery of smell and taste functions occurred in 52% and 61.5%, respectively. However, dysfunction persisted in 48%–38.5% of patients.
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spelling pubmed-80559242021-04-20 Eight-month follow-up of olfactory and gustatory dysfunctions in recovered COVID-19 patients Biadsee, Ameen Dagan, Or Ormianer, Zeev Kassem, Firas Masarwa, Shchada Biadsee, Ameer Am J Otolaryngol Article PURPOSE: To investigate the recovery of loss of smell and taste among recovered COVID-19 patients. MATERIALS AND METHODS: This cross-sectional follow-up study is a sequel to a study by Biadsee et al. Among the previous study population of 128 non-hospitalized patients, positive for COVID-19 by reverse transcription-polymerase chain reaction (RT-PCR), 97 patients participated in a survey designed for this study. Information and data regarding loss of smell and taste, rate of recovery, xerostomia, and additional symptoms; (Cough, Myalgia, Weakness, Rhinorrhea, Nasal congestion) were collected. RESULTS: A total of 43 men and 54 women were included. Mean age was 37.5 years (range 19–74). Mean follow-up was 229 days (range 191–253). Sixty-five patients reported gustatory dysfunction during the disease of which 61.5% reported full recovery, 38.5% partial recovery. Of 65 patients who reported olfactory impairment during the disease, 52% had full recovery and 48% reported partial recovery of olfactory function. Complete recovery of olfactory function was positively associated with full recovery of gustatory function (p = 0.01). Gender did not significantly affect the recovery of OD and GD (p = 0.45, p = 0.90, respectively). Patients who experienced olfactory dysfunction as an initial symptom had lower rates of olfactory complete recovery (p = 0.043). CONCLUSION: After a mean follow-up of 229 days, complete recovery of smell and taste functions occurred in 52% and 61.5%, respectively. However, dysfunction persisted in 48%–38.5% of patients. Elsevier Inc. 2021 2021-04-20 /pmc/articles/PMC8055924/ /pubmed/33894627 http://dx.doi.org/10.1016/j.amjoto.2021.103065 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Biadsee, Ameen
Dagan, Or
Ormianer, Zeev
Kassem, Firas
Masarwa, Shchada
Biadsee, Ameer
Eight-month follow-up of olfactory and gustatory dysfunctions in recovered COVID-19 patients
title Eight-month follow-up of olfactory and gustatory dysfunctions in recovered COVID-19 patients
title_full Eight-month follow-up of olfactory and gustatory dysfunctions in recovered COVID-19 patients
title_fullStr Eight-month follow-up of olfactory and gustatory dysfunctions in recovered COVID-19 patients
title_full_unstemmed Eight-month follow-up of olfactory and gustatory dysfunctions in recovered COVID-19 patients
title_short Eight-month follow-up of olfactory and gustatory dysfunctions in recovered COVID-19 patients
title_sort eight-month follow-up of olfactory and gustatory dysfunctions in recovered covid-19 patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055924/
https://www.ncbi.nlm.nih.gov/pubmed/33894627
http://dx.doi.org/10.1016/j.amjoto.2021.103065
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