GAMER-MRI in Multiple Sclerosis Identifies the Diffusion-Based Microstructural Measures That Are Most Sensitive to Focal Damage: A Deep-Learning-Based Analysis and Clinico-Biological Validation

Conventional magnetic resonance imaging (cMRI) in multiple sclerosis (MS) patients provides measures of focal brain damage and activity, which are fundamental for disease diagnosis, prognosis, and the evaluation of response to therapy. However, cMRI is insensitive to the damage to the microenvironme...

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Detalles Bibliográficos
Autores principales: Lu, Po-Jui, Barakovic, Muhamed, Weigel, Matthias, Rahmanzadeh, Reza, Galbusera, Riccardo, Schiavi, Simona, Daducci, Alessandro, La Rosa, Francesco, Bach Cuadra, Meritxell, Sandkühler, Robin, Kuhle, Jens, Kappos, Ludwig, Cattin, Philippe, Granziera, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8055933/
https://www.ncbi.nlm.nih.gov/pubmed/33889069
http://dx.doi.org/10.3389/fnins.2021.647535

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