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Enhancement and Imputation of Peak Signal Enables Accurate Cell-Type Classification in scATAC-seq

Single-cell Assay Transposase Accessible Chromatin sequencing (scATAC-seq) has been widely used in profiling genome-wide chromatin accessibility in thousands of individual cells. However, compared with single-cell RNA-seq, the peaks of scATAC-seq are much sparser due to the lower copy numbers (diplo...

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Detalles Bibliográficos
Autores principales:	Cui, Zhe, Cui, Ya, Gao, Yan, Jiang, Tao, Zang, Tianyi, Wang, Yadong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056015/ https://www.ncbi.nlm.nih.gov/pubmed/33889181 http://dx.doi.org/10.3389/fgene.2021.658352

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