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Cerebrospinal Fluid Neurofilament Light Chain (NfL) Predicts Disease Aggressiveness in Amyotrophic Lateral Sclerosis: An Application of the D50 Disease Progression Model

Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disorder. As previous therapeutic trials in ALS have been severely hampered by patients’ heterogeneity, the identification of biomarkers that reliably reflect disease progression represents a priority in ALS research...

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Detalles Bibliográficos
Autores principales:	Dreger, Marie, Steinbach, Robert, Gaur, Nayana, Metzner, Klara, Stubendorff, Beatrice, Witte, Otto W., Grosskreutz, Julian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056017/ https://www.ncbi.nlm.nih.gov/pubmed/33889072 http://dx.doi.org/10.3389/fnins.2021.651651

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