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The Human Cytomegalovirus UL116 Glycoprotein Is a Chaperone to Control gH-Based Complexes Levels on Virions

Human cytomegalovirus (HCMV) relies in large part upon the viral membrane fusion glycoprotein B and two alternative gH/gL complexes, gH/gL/gO (Trimer) and gH/gL/UL128/UL130/UL131A (Pentamer) to enter into cells. The relative amounts of Trimer and Pentamer vary among HCMV strains and contribute to di...

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Detalles Bibliográficos
Autores principales: Vezzani, Giacomo, Amendola, Diego, Yu, Dong, Chandramouli, Sumana, Frigimelica, Elisabetta, Maione, Domenico, Merola, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056026/
https://www.ncbi.nlm.nih.gov/pubmed/33889136
http://dx.doi.org/10.3389/fmicb.2021.630121