Inhibition of transforming growth factor-beta by Tranilast reduces tumor growth and ameliorates fibrosis in colorectal cancer

Transforming Growth Factor-beta (TGF-β) is dysregulated in colorectal cancer and there is growing evidence that it is associated with a poor prognosis and chemo-resistance in several malignances, including CRC. In this study we have explored the therapeutic potential of targeting TGF-β using Tranila...

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Detalles Bibliográficos
Autores principales: Hashemzehi, Milad, Yavari, Negar, Rahmani, Farzad, Asgharzadeh, Fereshteh, Soleimani, Atena, Shakour, Neda, Avan, Amir, Hadizadeh, Farzin, Fakhraie, Maryam, Marjaneh, Reyhaneh Moradi, Ferns, Gordon A., Reisi, Parham, Ryzhikov, Mikhail, Khazaei, Majid, Hassanian, Seyed Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056055/
https://www.ncbi.nlm.nih.gov/pubmed/33883985
http://dx.doi.org/10.17179/excli2020-2932

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