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Angiotensin receptor blocker Losartan inhibits tumor growth of colorectal cancer

The renin-angiotensin system (RAS) is up-regulated in patients with colorectal cancer (CRC) and is reported to be associated with poor prognosis and chemo-resistance. Here we explored the therapeutic potential of targeting RAS in CRC using Losartan, an angiotensin receptor blocker. An integrative-sy...

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Detalles Bibliográficos
Autores principales:	Hashemzehi, Milad, Rahmani, Farzad, Khoshakhlagh, Mahdieh, Avan, Amir, Asgharzadeh, Fereshteh, Barneh, Farnaz, Moradi-Marjaneh, Reyhaneh, Soleimani, Atena, Fiuji, Hamid, Ferns, Gordon A., Ryzhikov, Mikhail, Jafari, Mohieddin, Khazaei, Majid, Hassanian, Seyed Mahdi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Leibniz Research Centre for Working Environment and Human Factors 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056058/ https://www.ncbi.nlm.nih.gov/pubmed/33883980 http://dx.doi.org/10.17179/excli2020-3083

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