Cargando…
Mutations in the SARS-CoV-2 spike protein modulate the virus affinity to the human ACE2 receptor, an in silico analysis
The increasing number of SARS-CoV-2 variants associated with highly transmissible phenotypes is a health-public concern in the current pandemic scenario. Herein, we developed a comprehensive in silico analysis of the changes occurring upon mutations in the viral spike. We focused on mutants located...
Autores principales: | Ortega, Joseph Thomas, Pujol, Flor Helene, Jastrzebska, Beata, Rangel, Hector R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056063/ https://www.ncbi.nlm.nih.gov/pubmed/33883984 http://dx.doi.org/10.17179/excli2021-3471 |
Ejemplares similares
-
Omicron SARS-CoV-2 Variant Spike Protein Shows an Increased Affinity to the Human ACE2 Receptor: An In Silico Analysis
por: Ortega, Joseph Thomas, et al.
Publicado: (2021) -
Role of changes in SARS-CoV-2 spike protein in the interaction with the human ACE2 receptor: An in silico analysis
por: Ortega, Joseph Thomas, et al.
Publicado: (2020) -
In silico comparison of SARS-CoV-2 spike protein-ACE2 binding affinities across species and implications for virus origin
por: Piplani, Sakshi, et al.
Publicado: (2021) -
Impact of temperature on the affinity of SARS-CoV-2 Spike glycoprotein for host ACE2
por: Prévost, Jérémie, et al.
Publicado: (2021) -
Noneffect of SARS-CoV-2 spike glycoprotein Y217N mutation on affinity between the virus and ACE2
por: Hayashi, Takuma, et al.
Publicado: (2021)