Dl-butylphthalide inhibits rotenone-induced oxidative stress in microglia via regulation of the Keap1/Nrf2/HO-1 signaling pathway

Activated microglia are a source of superoxide which often increases oxidative stress in the brain microenvironment, increase production of reactive oxygen species (ROS) and directly or indirectly lead to dopaminergic neuronal death in the substantia nigra. Thus superoxide contributes to the pathoge...

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Detalles Bibliográficos
Autores principales: Luo, Rixin, Zhu, Lihong, Zeng, Zhaohao, Zhou, Ruiyi, Zhang, Jiawei, Xiao, Shu, Bi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056112/
https://www.ncbi.nlm.nih.gov/pubmed/33884035
http://dx.doi.org/10.3892/etm.2021.10029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056112/
https://www.ncbi.nlm.nih.gov/pubmed/33884035
http://dx.doi.org/10.3892/etm.2021.10029

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