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First line of defence: Skin microbiota may protect anurans from infective larval lungworms

Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gau...

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Detalles Bibliográficos
Autores principales: Christian, Keith, Shine, Richard, Day, Kimberley A., Kaestli, Mirjam, Gibb, Karen, Shilton, Catherine M., Brown, Gregory P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056135/
https://www.ncbi.nlm.nih.gov/pubmed/33898219
http://dx.doi.org/10.1016/j.ijppaw.2021.02.014
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author Christian, Keith
Shine, Richard
Day, Kimberley A.
Kaestli, Mirjam
Gibb, Karen
Shilton, Catherine M.
Brown, Gregory P.
author_facet Christian, Keith
Shine, Richard
Day, Kimberley A.
Kaestli, Mirjam
Gibb, Karen
Shilton, Catherine M.
Brown, Gregory P.
author_sort Christian, Keith
collection PubMed
description Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gauze resulted in threefold higher rates of infection by lungworms (Rhabdias pseudosphaerocephala) following standardised exposure to infective skin-penetrating larvae. Higher concentrations of microbial DNA were associated with lower rates of lungworm entry. Our data suggest that microbial activity on the anuran skin comprises an important line of defence against attack by macroparasites as well as by fungi and other microbes.
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spelling pubmed-80561352021-04-23 First line of defence: Skin microbiota may protect anurans from infective larval lungworms Christian, Keith Shine, Richard Day, Kimberley A. Kaestli, Mirjam Gibb, Karen Shilton, Catherine M. Brown, Gregory P. Int J Parasitol Parasites Wildl Regular Article Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gauze resulted in threefold higher rates of infection by lungworms (Rhabdias pseudosphaerocephala) following standardised exposure to infective skin-penetrating larvae. Higher concentrations of microbial DNA were associated with lower rates of lungworm entry. Our data suggest that microbial activity on the anuran skin comprises an important line of defence against attack by macroparasites as well as by fungi and other microbes. Elsevier 2021-03-03 /pmc/articles/PMC8056135/ /pubmed/33898219 http://dx.doi.org/10.1016/j.ijppaw.2021.02.014 Text en © 2021 The Authors. Published by Elsevier Ltd on behalf of Australian Society for Parasitology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Regular Article
Christian, Keith
Shine, Richard
Day, Kimberley A.
Kaestli, Mirjam
Gibb, Karen
Shilton, Catherine M.
Brown, Gregory P.
First line of defence: Skin microbiota may protect anurans from infective larval lungworms
title First line of defence: Skin microbiota may protect anurans from infective larval lungworms
title_full First line of defence: Skin microbiota may protect anurans from infective larval lungworms
title_fullStr First line of defence: Skin microbiota may protect anurans from infective larval lungworms
title_full_unstemmed First line of defence: Skin microbiota may protect anurans from infective larval lungworms
title_short First line of defence: Skin microbiota may protect anurans from infective larval lungworms
title_sort first line of defence: skin microbiota may protect anurans from infective larval lungworms
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056135/
https://www.ncbi.nlm.nih.gov/pubmed/33898219
http://dx.doi.org/10.1016/j.ijppaw.2021.02.014
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