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First line of defence: Skin microbiota may protect anurans from infective larval lungworms
Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gau...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056135/ https://www.ncbi.nlm.nih.gov/pubmed/33898219 http://dx.doi.org/10.1016/j.ijppaw.2021.02.014 |
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author | Christian, Keith Shine, Richard Day, Kimberley A. Kaestli, Mirjam Gibb, Karen Shilton, Catherine M. Brown, Gregory P. |
author_facet | Christian, Keith Shine, Richard Day, Kimberley A. Kaestli, Mirjam Gibb, Karen Shilton, Catherine M. Brown, Gregory P. |
author_sort | Christian, Keith |
collection | PubMed |
description | Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gauze resulted in threefold higher rates of infection by lungworms (Rhabdias pseudosphaerocephala) following standardised exposure to infective skin-penetrating larvae. Higher concentrations of microbial DNA were associated with lower rates of lungworm entry. Our data suggest that microbial activity on the anuran skin comprises an important line of defence against attack by macroparasites as well as by fungi and other microbes. |
format | Online Article Text |
id | pubmed-8056135 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-80561352021-04-23 First line of defence: Skin microbiota may protect anurans from infective larval lungworms Christian, Keith Shine, Richard Day, Kimberley A. Kaestli, Mirjam Gibb, Karen Shilton, Catherine M. Brown, Gregory P. Int J Parasitol Parasites Wildl Regular Article Functional roles of the rich microbiota of the skin are not fully understood, but include protection against microbial diseases and other environmental challenges. In experimental studies, we show that reducing the microbiota from cane toad (Rhinella marina) skin by gently wiping with absorptive gauze resulted in threefold higher rates of infection by lungworms (Rhabdias pseudosphaerocephala) following standardised exposure to infective skin-penetrating larvae. Higher concentrations of microbial DNA were associated with lower rates of lungworm entry. Our data suggest that microbial activity on the anuran skin comprises an important line of defence against attack by macroparasites as well as by fungi and other microbes. Elsevier 2021-03-03 /pmc/articles/PMC8056135/ /pubmed/33898219 http://dx.doi.org/10.1016/j.ijppaw.2021.02.014 Text en © 2021 The Authors. Published by Elsevier Ltd on behalf of Australian Society for Parasitology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Regular Article Christian, Keith Shine, Richard Day, Kimberley A. Kaestli, Mirjam Gibb, Karen Shilton, Catherine M. Brown, Gregory P. First line of defence: Skin microbiota may protect anurans from infective larval lungworms |
title | First line of defence: Skin microbiota may protect anurans from infective larval lungworms |
title_full | First line of defence: Skin microbiota may protect anurans from infective larval lungworms |
title_fullStr | First line of defence: Skin microbiota may protect anurans from infective larval lungworms |
title_full_unstemmed | First line of defence: Skin microbiota may protect anurans from infective larval lungworms |
title_short | First line of defence: Skin microbiota may protect anurans from infective larval lungworms |
title_sort | first line of defence: skin microbiota may protect anurans from infective larval lungworms |
topic | Regular Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056135/ https://www.ncbi.nlm.nih.gov/pubmed/33898219 http://dx.doi.org/10.1016/j.ijppaw.2021.02.014 |
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