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Application of fluorescent-based technology detecting protein-protein interactions to monitor the binding of hepatitis B virus X protein to DNA-damage-binding protein 1

The hepatitis B virus X protein (HBx) and the V protein of paramyxovirus simian virus 5 (SV5-V) interact with DNA damage-binding protein 1 (DDB1), a cellular enzyme involved in DNA repair and cell cycle regulation, to stimulate viral activity. DDB1 has several cellular substrates, and the amino acid...

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Detalles Bibliográficos
Autores principales:	Omagari, Katsumi, Asamitsu, Kaori, Tanaka, Yasuhito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society of Japan 2021
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056151/ https://www.ncbi.nlm.nih.gov/pubmed/33977004 http://dx.doi.org/10.2142/biophysico.bppb-v18.008

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