Potent suppression of hydrophobic bile acids by aldafermin, an FGF19 analogue, across metabolic and cholestatic liver diseases

BACKGROUND & AIMS: Higher serum bile acid levels are associated with an increased risk of cirrhosis and liver-related morbidity and mortality. Herein, we report secondary analyses of aldafermin, an engineered analogue of the gut hormone fibroblast growth factor 19, on the circulating bile acid p...

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Detalles Bibliográficos
Autores principales: Sanyal, Arun J., Ling, Lei, Beuers, Ulrich, DePaoli, Alex M., Lieu, Hsiao D., Harrison, Stephen A., Hirschfield, Gideon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056274/
https://www.ncbi.nlm.nih.gov/pubmed/33898959
http://dx.doi.org/10.1016/j.jhepr.2021.100255

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