SAHA is neuroprotective in in vitro and in situ models of retinitis pigmentosa

Purpose: Recent reports linking HDAC6 to mitochondrial turnover and neurodegeneration led us to hypothesize that an inhibitor such as Vorinostat (suberoylanilide hydroxamic acid, SAHA) may reduce mitochondrial damage found in retinitis pigmentosa (RP), a progressive neurodegenerative disease of the...

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Detalles Bibliográficos
Autores principales: Perron, Nathan R., Nasarre, Cécile, Bandyopadhyay, Mausumi, Beeson, Craig C., Rohrer, Baerbel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056468/
https://www.ncbi.nlm.nih.gov/pubmed/33907370

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