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ATP and NADPH engineering of Escherichia coli to improve the production of 4-hydroxyphenylacetic acid using CRISPRi

BACKGROUND: 4-Hydroxyphenylacetic acid (4HPAA) is an important raw material for the synthesis of drugs, pesticides and biochemicals. Microbial biotechnology would be an attractive approach for 4HPAA production, and cofactors play an important role in biosynthesis. RESULTS: We developed a novel strat...

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Detalles Bibliográficos
Autores principales:	Shen, Yu-Ping, Liao, Yu-Ling, Lu, Qian, He, Xin, Yan, Zhi-Bo, Liu, Jian-Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056492/ https://www.ncbi.nlm.nih.gov/pubmed/33879249 http://dx.doi.org/10.1186/s13068-021-01954-6

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