Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging

BACKGROUND: Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer’s disease (AD). This work aimed to determine if and when distribution volume ratio (DVR; derived from dynamic...

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Detalles Bibliográficos
Autores principales: Lopes Alves, Isadora, Heeman, Fiona, Collij, Lyduine E., Salvadó, Gemma, Tolboom, Nelleke, Vilor-Tejedor, Natàlia, Markiewicz, Pawel, Yaqub, Maqsood, Cash, David, Mormino, Elizabeth C., Insel, Philip S., Boellaard, Ronald, van Berckel, Bart N. M., Lammertsma, Adriaan A., Barkhof, Frederik, Gispert, Juan Domingo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056524/
https://www.ncbi.nlm.nih.gov/pubmed/33875021
http://dx.doi.org/10.1186/s13195-021-00819-2

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