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Association of body mass index and waist circumference with high blood pressure in older adults

BACKGROUND: The relationship between obesity and prevalent high blood pressure in older adults has predominantly been estimated using categorical measures of body mass index (BMI) and waist circumference (WC), masking the shape of the dose-response relationship. We aimed to examine the precise relat...

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Autores principales: Zhang, Wenli, He, Kun, Zhao, Hao, Hu, Xueqi, Yin, Chunyu, Zhao, Xiaoyan, Shi, Songhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056549/
https://www.ncbi.nlm.nih.gov/pubmed/33874889
http://dx.doi.org/10.1186/s12877-021-02154-5
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author Zhang, Wenli
He, Kun
Zhao, Hao
Hu, Xueqi
Yin, Chunyu
Zhao, Xiaoyan
Shi, Songhe
author_facet Zhang, Wenli
He, Kun
Zhao, Hao
Hu, Xueqi
Yin, Chunyu
Zhao, Xiaoyan
Shi, Songhe
author_sort Zhang, Wenli
collection PubMed
description BACKGROUND: The relationship between obesity and prevalent high blood pressure in older adults has predominantly been estimated using categorical measures of body mass index (BMI) and waist circumference (WC), masking the shape of the dose-response relationship. We aimed to examine the precise relationship of BMI, WC with high blood pressure and to assess the appropriate level of BMI and WC for high blood pressure. METHODS: We examined data for 126,123 individuals in Xinzheng city aged ≥60 years from a population based study from January to December 2019. Logistic regression and restricted cubic spline models were applied to assess the relationship and the appropriate level of BMI and WC for high blood pressure. An additive interaction analysis was used to test synergistic effects between a higher BMI and WC for high blood pressure. RESULTS: The full-adjusted odds ratios (ORs) with 95% confidence intervals (CIs) of an increase of 1 kg/m(2) in BMI and 1 cm in WC for high blood pressure were 1.084 (1.080–1.087) and 1.026(1.024–1.027), respectively. Multivariable adjusted restricted cubic spline analyses showed the nonlinear relationships of BMI and WC with high blood pressure in both men and women (all P < 0.001). The risk of high blood pressure increased steeply with increasing BMI from ≥25 kg/m(2) and WC ≥ 88 cm or 86 cm for males and females, respectively. And we observed a significant additive interaction between a higher BMI and WC such that the prevalence of high blood pressure was significantly enhanced. CONCLUSION: These findings suggest increased high blood pressure prevalence in the older adults with increased BMI and WC. BMI ≤ 25 kg/m2 and WC ≤ 88 cm or 86 cm for males and females may be the best suggestion with regard to primary prevention of high blood pressure in older adults. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-021-02154-5.
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spelling pubmed-80565492021-04-20 Association of body mass index and waist circumference with high blood pressure in older adults Zhang, Wenli He, Kun Zhao, Hao Hu, Xueqi Yin, Chunyu Zhao, Xiaoyan Shi, Songhe BMC Geriatr Research Article BACKGROUND: The relationship between obesity and prevalent high blood pressure in older adults has predominantly been estimated using categorical measures of body mass index (BMI) and waist circumference (WC), masking the shape of the dose-response relationship. We aimed to examine the precise relationship of BMI, WC with high blood pressure and to assess the appropriate level of BMI and WC for high blood pressure. METHODS: We examined data for 126,123 individuals in Xinzheng city aged ≥60 years from a population based study from January to December 2019. Logistic regression and restricted cubic spline models were applied to assess the relationship and the appropriate level of BMI and WC for high blood pressure. An additive interaction analysis was used to test synergistic effects between a higher BMI and WC for high blood pressure. RESULTS: The full-adjusted odds ratios (ORs) with 95% confidence intervals (CIs) of an increase of 1 kg/m(2) in BMI and 1 cm in WC for high blood pressure were 1.084 (1.080–1.087) and 1.026(1.024–1.027), respectively. Multivariable adjusted restricted cubic spline analyses showed the nonlinear relationships of BMI and WC with high blood pressure in both men and women (all P < 0.001). The risk of high blood pressure increased steeply with increasing BMI from ≥25 kg/m(2) and WC ≥ 88 cm or 86 cm for males and females, respectively. And we observed a significant additive interaction between a higher BMI and WC such that the prevalence of high blood pressure was significantly enhanced. CONCLUSION: These findings suggest increased high blood pressure prevalence in the older adults with increased BMI and WC. BMI ≤ 25 kg/m2 and WC ≤ 88 cm or 86 cm for males and females may be the best suggestion with regard to primary prevention of high blood pressure in older adults. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12877-021-02154-5. BioMed Central 2021-04-19 /pmc/articles/PMC8056549/ /pubmed/33874889 http://dx.doi.org/10.1186/s12877-021-02154-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Zhang, Wenli
He, Kun
Zhao, Hao
Hu, Xueqi
Yin, Chunyu
Zhao, Xiaoyan
Shi, Songhe
Association of body mass index and waist circumference with high blood pressure in older adults
title Association of body mass index and waist circumference with high blood pressure in older adults
title_full Association of body mass index and waist circumference with high blood pressure in older adults
title_fullStr Association of body mass index and waist circumference with high blood pressure in older adults
title_full_unstemmed Association of body mass index and waist circumference with high blood pressure in older adults
title_short Association of body mass index and waist circumference with high blood pressure in older adults
title_sort association of body mass index and waist circumference with high blood pressure in older adults
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056549/
https://www.ncbi.nlm.nih.gov/pubmed/33874889
http://dx.doi.org/10.1186/s12877-021-02154-5
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