Off-label use of anti-IL-1 drugs in rheumatic diseases

Interleukin-1 (IL-1) plays a key role in the pathogenesis of different rheumatic diseases. There are now several agents available on the market capable of blocking IL-1. The proven effectiveness and excellent safety of these drugs makes them a possible therapeutic option in the treatment of IL-1 dri...

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Autores principales: Stefania, Silvia, Colia, Ripalta, Cinzia, Rotondo, Corrado, Addolorata, Cantatore, Francesco Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056561/
https://www.ncbi.nlm.nih.gov/pubmed/33855881
http://dx.doi.org/10.1177/20587384211006584
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author Stefania, Silvia
Colia, Ripalta
Cinzia, Rotondo
Corrado, Addolorata
Cantatore, Francesco Paolo
author_facet Stefania, Silvia
Colia, Ripalta
Cinzia, Rotondo
Corrado, Addolorata
Cantatore, Francesco Paolo
author_sort Stefania, Silvia
collection PubMed
description Interleukin-1 (IL-1) plays a key role in the pathogenesis of different rheumatic diseases. There are now several agents available on the market capable of blocking IL-1. The proven effectiveness and excellent safety of these drugs makes them a possible therapeutic option in the treatment of IL-1 driven diseases, when previous therapies are contraindicated or ineffective. This article discusses the European wide off-label use of these drugs for the treatment of rheumatic diseases.
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spelling pubmed-80565612021-05-04 Off-label use of anti-IL-1 drugs in rheumatic diseases Stefania, Silvia Colia, Ripalta Cinzia, Rotondo Corrado, Addolorata Cantatore, Francesco Paolo Int J Immunopathol Pharmacol Original Research Article Interleukin-1 (IL-1) plays a key role in the pathogenesis of different rheumatic diseases. There are now several agents available on the market capable of blocking IL-1. The proven effectiveness and excellent safety of these drugs makes them a possible therapeutic option in the treatment of IL-1 driven diseases, when previous therapies are contraindicated or ineffective. This article discusses the European wide off-label use of these drugs for the treatment of rheumatic diseases. SAGE Publications 2021-04-15 /pmc/articles/PMC8056561/ /pubmed/33855881 http://dx.doi.org/10.1177/20587384211006584 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Stefania, Silvia
Colia, Ripalta
Cinzia, Rotondo
Corrado, Addolorata
Cantatore, Francesco Paolo
Off-label use of anti-IL-1 drugs in rheumatic diseases
title Off-label use of anti-IL-1 drugs in rheumatic diseases
title_full Off-label use of anti-IL-1 drugs in rheumatic diseases
title_fullStr Off-label use of anti-IL-1 drugs in rheumatic diseases
title_full_unstemmed Off-label use of anti-IL-1 drugs in rheumatic diseases
title_short Off-label use of anti-IL-1 drugs in rheumatic diseases
title_sort off-label use of anti-il-1 drugs in rheumatic diseases
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056561/
https://www.ncbi.nlm.nih.gov/pubmed/33855881
http://dx.doi.org/10.1177/20587384211006584
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AT corradoaddolorata offlabeluseofantiil1drugsinrheumaticdiseases
AT cantatorefrancescopaolo offlabeluseofantiil1drugsinrheumaticdiseases

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