High levels of anti-Leishmania IgG3 and low CD4(+) T cells count were associated with relapses in visceral leishmaniasis

BACKGROUND: Visceral leishmaniasis (VL) is severe and potentially fatal. Brazil is one of the countries with the greatest endemicity for the disease in the world. The reduction of CD4(+) T lymphocytes, B cells activation and high levels of inflammatory cytokines (IL-6/IL-8/TNF/IL-1β), plasma LPS, so...

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Detalles Bibliográficos
Autores principales: Kuschnir, Renata Caetano, Pereira, Leonardo Soares, Dutra, Maria Rita Teixeira, de Paula, Ludmila, Silva-Freitas, Maria Luciana, Corrêa-Castro, Gabriela, da Costa Cruz Silva, Simone, Cota, Glaucia, Santos-Oliveira, Joanna Reis, Da-Cruz, Alda Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056614/
https://www.ncbi.nlm.nih.gov/pubmed/33874901
http://dx.doi.org/10.1186/s12879-021-06051-5

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