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Advances in epigenetic therapeutics with focus on solid tumors
Epigenetic (“above genetics”) modifications can alter the gene expression without altering the DNA sequence. Aberrant epigenetic regulations in cancer include DNA methylation, histone methylation, histone acetylation, non-coding RNA, and mRNA methylation. Epigenetic-targeted agents have demonstrated...
Autores principales: | Jin, Ning, George, Tiffany L., Otterson, Gregory A., Verschraegen, Claire, Wen, Haitao, Carbone, David, Herman, James, Bertino, Erin M., He, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056722/ https://www.ncbi.nlm.nih.gov/pubmed/33879235 http://dx.doi.org/10.1186/s13148-021-01069-7 |
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