Cargando…
C5aR inhibition of nonimmune cells suppresses inflammation and maintains epithelial integrity in SARS-CoV-2–infected primary human airway epithelia
BACKGROUND: Excessive inflammation triggered by a hitherto undescribed mechanism is a hallmark of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections and is associated with enhanced pathogenicity and mortality. OBJECTIVE: Complement hyperactivation promotes lung injury and was ob...
Autores principales: | Posch, Wilfried, Vosper, Jonathan, Noureen, Asma, Zaderer, Viktoria, Witting, Christina, Bertacchi, Giulia, Gstir, Ronald, Filipek, Przemyslaw A., Bonn, Günther K., Huber, Lukas A., Bellmann-Weiler, Rosa, Lass-Flörl, Cornelia, Wilflingseder, Doris |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056780/ https://www.ncbi.nlm.nih.gov/pubmed/33852936 http://dx.doi.org/10.1016/j.jaci.2021.03.038 |
Ejemplares similares
-
ColdZyme Maintains Integrity in SARS-CoV-2-Infected Airway Epithelia
por: Posch, W., et al.
Publicado: (2021) -
ColdZyme® protects airway epithelia from infection with BA.4/5
por: Viktoria, Zaderer, et al.
Publicado: (2022) -
Correction: ColdZyme® protects airway epithelia from infection with BA.4/5
por: Zaderer, Viktoria, et al.
Publicado: (2023) -
Dexamethasone Promotes Aspergillus fumigatus Growth in Macrophages by Triggering M2 Repolarization via Targeting PKM2
por: Luvanda, Maureen K., et al.
Publicado: (2021) -
Dexamethasone Creates a Suppressive Microenvironment and Promotes Aspergillus fumigatus Invasion in a Human 3D Epithelial/Immune Respiratory Model
por: Luvanda, Maureen K., et al.
Publicado: (2021)