Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure

Airway closure is a physiological phenomenon in which the distal airways are obstructed when the airway pressure drops below the airway opening pressure. We assessed this phenomenon in 27 patients with coronavirus disease 2019-related acute respiratory distress syndrome. Twelve (44%) patients had an...

Descripción completa

Detalles Bibliográficos
Autores principales: Brault, Clément, Zerbib, Yoann, Kontar, Loay, Carpentier, Mathieu, Maizel, Julien, Slama, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056835/
https://www.ncbi.nlm.nih.gov/pubmed/33906102
http://dx.doi.org/10.1016/j.jcrc.2021.04.005
Descripción
Sumario:Airway closure is a physiological phenomenon in which the distal airways are obstructed when the airway pressure drops below the airway opening pressure. We assessed this phenomenon in 27 patients with coronavirus disease 2019-related acute respiratory distress syndrome. Twelve (44%) patients had an airway opening pressure above 5 cmH(2)O. The median airway opening pressure was 8 cmH(2)O (interquartile range, 7–10), with a maximum value of 17 cmH(2)O. Three patients had a baseline positive end-expiratory pressure lower than the airway opening pressure.

Ejemplares similares