Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure

Airway closure is a physiological phenomenon in which the distal airways are obstructed when the airway pressure drops below the airway opening pressure. We assessed this phenomenon in 27 patients with coronavirus disease 2019-related acute respiratory distress syndrome. Twelve (44%) patients had an...

Descripción completa

Detalles Bibliográficos
Autores principales: Brault, Clément, Zerbib, Yoann, Kontar, Loay, Carpentier, Mathieu, Maizel, Julien, Slama, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056835/
https://www.ncbi.nlm.nih.gov/pubmed/33906102
http://dx.doi.org/10.1016/j.jcrc.2021.04.005
_version_ 1783680731369701376
author Brault, Clément
Zerbib, Yoann
Kontar, Loay
Carpentier, Mathieu
Maizel, Julien
Slama, Michel
author_facet Brault, Clément
Zerbib, Yoann
Kontar, Loay
Carpentier, Mathieu
Maizel, Julien
Slama, Michel
author_sort Brault, Clément
collection PubMed
description Airway closure is a physiological phenomenon in which the distal airways are obstructed when the airway pressure drops below the airway opening pressure. We assessed this phenomenon in 27 patients with coronavirus disease 2019-related acute respiratory distress syndrome. Twelve (44%) patients had an airway opening pressure above 5 cmH(2)O. The median airway opening pressure was 8 cmH(2)O (interquartile range, 7–10), with a maximum value of 17 cmH(2)O. Three patients had a baseline positive end-expiratory pressure lower than the airway opening pressure.
format Online
Article
Text
id pubmed-8056835
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-80568352021-04-20 Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure Brault, Clément Zerbib, Yoann Kontar, Loay Carpentier, Mathieu Maizel, Julien Slama, Michel J Crit Care Article Airway closure is a physiological phenomenon in which the distal airways are obstructed when the airway pressure drops below the airway opening pressure. We assessed this phenomenon in 27 patients with coronavirus disease 2019-related acute respiratory distress syndrome. Twelve (44%) patients had an airway opening pressure above 5 cmH(2)O. The median airway opening pressure was 8 cmH(2)O (interquartile range, 7–10), with a maximum value of 17 cmH(2)O. Three patients had a baseline positive end-expiratory pressure lower than the airway opening pressure. Elsevier Inc. 2021-08 2021-04-20 /pmc/articles/PMC8056835/ /pubmed/33906102 http://dx.doi.org/10.1016/j.jcrc.2021.04.005 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Brault, Clément
Zerbib, Yoann
Kontar, Loay
Carpentier, Mathieu
Maizel, Julien
Slama, Michel
Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure
title Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure
title_full Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure
title_fullStr Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure
title_full_unstemmed Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure
title_short Positive end-expiratory pressure in COVID-19-related ARDS: Do not forget the airway closure
title_sort positive end-expiratory pressure in covid-19-related ards: do not forget the airway closure
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056835/
https://www.ncbi.nlm.nih.gov/pubmed/33906102
http://dx.doi.org/10.1016/j.jcrc.2021.04.005
work_keys_str_mv AT braultclement positiveendexpiratorypressureincovid19relatedardsdonotforgettheairwayclosure
AT zerbibyoann positiveendexpiratorypressureincovid19relatedardsdonotforgettheairwayclosure
AT kontarloay positiveendexpiratorypressureincovid19relatedardsdonotforgettheairwayclosure
AT carpentiermathieu positiveendexpiratorypressureincovid19relatedardsdonotforgettheairwayclosure
AT maizeljulien positiveendexpiratorypressureincovid19relatedardsdonotforgettheairwayclosure
AT slamamichel positiveendexpiratorypressureincovid19relatedardsdonotforgettheairwayclosure

Ejemplares similares