An α2,3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses

A glycopolymer bearing α2,3-linked sialyltrisaccharides was synthesized by living radical polymerization using a glycomonomer prepared by a protecting-group-free process, direct azidation of the free sialyllactose, and subsequent azide-alkyne cycloaddition. The prepared glycopolymer with pendant 3´-...

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Autores principales: Tanaka, Tomonari, Zhou, Yiting, Tamoto, Chihiro, Kurebayashi, Yuuki, Takahashi, Tadanobu, Suzuki, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Applied Glycoscience 2017
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056908/
https://www.ncbi.nlm.nih.gov/pubmed/34354496
http://dx.doi.org/10.5458/jag.jag.JAG-2017_003
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author Tanaka, Tomonari
Zhou, Yiting
Tamoto, Chihiro
Kurebayashi, Yuuki
Takahashi, Tadanobu
Suzuki, Takashi
author_facet Tanaka, Tomonari
Zhou, Yiting
Tamoto, Chihiro
Kurebayashi, Yuuki
Takahashi, Tadanobu
Suzuki, Takashi
author_sort Tanaka, Tomonari
collection PubMed
description A glycopolymer bearing α2,3-linked sialyltrisaccharides was synthesized by living radical polymerization using a glycomonomer prepared by a protecting-group-free process, direct azidation of the free sialyllactose, and subsequent azide-alkyne cycloaddition. The prepared glycopolymer with pendant 3´-sialyllactose moieties strongly interacted with both avian and human influenza viruses analyzed by the hemagglutination inhibition assay and the quartz crystal microbalance method.
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spelling pubmed-80569082021-08-04 An α2,3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses Tanaka, Tomonari Zhou, Yiting Tamoto, Chihiro Kurebayashi, Yuuki Takahashi, Tadanobu Suzuki, Takashi J Appl Glycosci (1999) Note A glycopolymer bearing α2,3-linked sialyltrisaccharides was synthesized by living radical polymerization using a glycomonomer prepared by a protecting-group-free process, direct azidation of the free sialyllactose, and subsequent azide-alkyne cycloaddition. The prepared glycopolymer with pendant 3´-sialyllactose moieties strongly interacted with both avian and human influenza viruses analyzed by the hemagglutination inhibition assay and the quartz crystal microbalance method. The Japanese Society of Applied Glycoscience 2017-05-20 /pmc/articles/PMC8056908/ /pubmed/34354496 http://dx.doi.org/10.5458/jag.jag.JAG-2017_003 Text en 2017 by The Japanese Society of Applied Glycoscience https://creativecommons.org/licenses/by-nc/4.0/This is an open-access paper distributed under the terms of the Creative Commons Attribution Non-Commercial (by-nc) License (CC-BY-NC4.0: https://creativecommons.org/licenses/by-nc/4.0/).
spellingShingle Note
Tanaka, Tomonari
Zhou, Yiting
Tamoto, Chihiro
Kurebayashi, Yuuki
Takahashi, Tadanobu
Suzuki, Takashi
An α2,3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses
title An α2,3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses
title_full An α2,3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses
title_fullStr An α2,3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses
title_full_unstemmed An α2,3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses
title_short An α2,3-Linked Sialylglycopolymer as a Multivalent Glycoligand Against Avian and Human Influenza Viruses
title_sort α2,3-linked sialylglycopolymer as a multivalent glycoligand against avian and human influenza viruses
topic Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056908/
https://www.ncbi.nlm.nih.gov/pubmed/34354496
http://dx.doi.org/10.5458/jag.jag.JAG-2017_003
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