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Vigilant: An Engineered VirD2-Cas9 Complex for Lateral Flow Assay-Based Detection of SARS-CoV2

[Image: see text] Rapid, sensitive, and specific point-of-care testing for pathogens is crucial for disease control. Lateral flow assays (LFAs) have been employed for nucleic acid detection, but they have limited sensitivity and specificity. Here, we used a fusion of catalytically inactive SpCas9 en...

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Detalles Bibliográficos
Autores principales:	Marsic, Tin, Ali, Zahir, Tehseen, Muhammad, Mahas, Ahmed, Hamdan, Samir, Mahfouz, Magdy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056947/ https://www.ncbi.nlm.nih.gov/pubmed/33844549 http://dx.doi.org/10.1021/acs.nanolett.1c00612

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