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Novel Flow Cytometric Immunoassay for Detection of Proinsulin Autoantibodies in Diabetes Mellitus Employing a Recombinant Autoantigen Expressed in E. coli

INTRODUCTION: Insulin and proinsulin autoantibodies (IAA/PAA) are usually the first markers to appear in patients with type 1 Diabetes Mellitus (T1DM) and their prevalence ranges from 10 to 60% in the child-adolescent population. The reference method for IAA/PAA detection is the Radioligand Binding...

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Detalles Bibliográficos
Autores principales:	Sabljic, Adriana Victoria, Bombicino, Silvina Sonia, Marfía, Juan Ignacio, Guerra, Luciano Lucas, Steinhardt, Alberto Penas, Faccinetti, Natalia Inés, Iacono, Rubén Francisco, Poskus, Edgardo, Trabucchi, Aldana, Valdez, Silvina Noemí
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056981/ https://www.ncbi.nlm.nih.gov/pubmed/33889155 http://dx.doi.org/10.3389/fimmu.2021.648021

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