GILZ Regulates the Expression of Pro-Inflammatory Cytokines and Protects Against End-Organ Damage in a Model of Lupus

Glucocorticoid-induced leucine zipper (GILZ) mimics many of the anti-inflammatory effects of glucocorticoids, suggesting it as a point of therapeutic intervention that could bypass GC adverse effects. We previously reported that GILZ down-regulation is a feature of human SLE, and loss of GILZ permit...

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Detalles Bibliográficos
Autores principales: Nataraja, Champa, Dankers, Wendy, Flynn, Jacqueline, Lee, Jacinta P. W., Zhu, Wendy, Vincent, Fabien B., Gearing, Linden J., Ooi, Joshua, Pervin, Mehnaz, Cristofaro, Megan A., Sherlock, Rochelle, Hasnat, Md Abul, Harris, James, Morand, Eric F., Jones, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8056982/
https://www.ncbi.nlm.nih.gov/pubmed/33889157
http://dx.doi.org/10.3389/fimmu.2021.652800

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