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Inflammatory Cytokine Profile and Plasticity of Brain and Spinal Microglia in Response to ATP and Glutamate

Microglia are the primary cells in the central nervous system that identify and respond to injury or damage. Such a perturbation in the nervous system induces the release of molecules including ATP and glutamate that act as damage-associated molecular patterns (DAMPs). DAMPs are detected by microgli...

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Detalles Bibliográficos
Autores principales: Jesudasan, Sam Joshva Baskar, Gupta, Somnath J., Churchward, Matthew A., Todd, Kathryn G., Winship, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057348/
https://www.ncbi.nlm.nih.gov/pubmed/33889075
http://dx.doi.org/10.3389/fncel.2021.634020