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Quantifying the heterogeneity of cognitive functioning in Alzheimer’s disease to extend the placebo-treatment dichotomy: Latent class analysis of individual-participant data from five pivotal randomized clinical trials of donepezil

BACKGROUND: The extent and profiles of heterogeneity in cognitive functioning among participants in clinical trials of antidementia medication are unknown. We aimed to quantify and identify profiles of heterogeneity of cognition in Alzheimer’s disease. METHODS: Individual-level participant data were...

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Detalles Bibliográficos
Autores principales:	Levine, Stephen Z., Goldberg, Yair, Yoshida, Kazufumi, Samara, Myrto, Cipriani, Andrea, Iwatsubo, Takeshi, Leucht, Stefan, Furawaka, Toshiaki A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057455/ https://www.ncbi.nlm.nih.gov/pubmed/33583479 http://dx.doi.org/10.1192/j.eurpsy.2021.8

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