Cargando…

Derivation and Internal Validation of a Prediction Model for Pediatric Hand Fracture Triage

BACKGROUND: Pediatric hand fractures are common, and most can be managed by a period of immobilization. However, it remains challenging to identify those more complex fractures requiring the expertise of a hand surgeon to ensure a good outcome. The purpose of this study was to develop a prediction m...

Descripción completa

Detalles Bibliográficos
Autores principales: Hartley, Rebecca L., Fraulin, Frankie O.G., Harrop, A. Robertson, Faris, Peter, Wick, James, Ronksley, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057756/
https://www.ncbi.nlm.nih.gov/pubmed/33889473
http://dx.doi.org/10.1097/GOX.0000000000003543
_version_ 1783680891387641856
author Hartley, Rebecca L.
Fraulin, Frankie O.G.
Harrop, A. Robertson
Faris, Peter
Wick, James
Ronksley, Paul E.
author_facet Hartley, Rebecca L.
Fraulin, Frankie O.G.
Harrop, A. Robertson
Faris, Peter
Wick, James
Ronksley, Paul E.
author_sort Hartley, Rebecca L.
collection PubMed
description BACKGROUND: Pediatric hand fractures are common, and most can be managed by a period of immobilization. However, it remains challenging to identify those more complex fractures requiring the expertise of a hand surgeon to ensure a good outcome. The purpose of this study was to develop a prediction model for identification of complex pediatric hand fractures requiring care by a hand surgeon. METHODS: A 2-year retrospective cohort study of consecutively referred pediatric (<18 years) hand fracture patients was used to derive and internally validate a prediction model for identification of complex fractures requiring the expertise of a hand surgeon. These complex fractures were defined as those that required surgery, closed reduction, or four or more appointments with a hand surgeon. The model, derived by multivariable logistic regression analysis, was internally validated using bootstrapping and then translated into a risk index. RESULTS: Of 1170 fractures, 416 (35.6%) met criteria for a complex fracture. Multivariable regression analysis identified six significant predictors of complex fracture: open fracture, rotational deformity, angulation, condylar involvement, dislocation or subluxation, and displacement. Internal validation demonstrated good performance of the model (C-statistic = 0.88, calibration curve p = 0.935). A threshold of ≥1 point (ie, any one of the predictors) resulted in a simple, easy-to-use tool with 96.4% sensitivity and 45.5% specificity. CONCLUSIONS: A high-performing and clinically useful decision support tool was developed for emergency and urgent care physicians providing initial assessment for children with hand fractures. This tool will provide the basis for development of a clinical care pathway for pediatric hand fractures.
format Online
Article
Text
id pubmed-8057756
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-80577562021-04-21 Derivation and Internal Validation of a Prediction Model for Pediatric Hand Fracture Triage Hartley, Rebecca L. Fraulin, Frankie O.G. Harrop, A. Robertson Faris, Peter Wick, James Ronksley, Paul E. Plast Reconstr Surg Glob Open Hand/Peripheral Nerve BACKGROUND: Pediatric hand fractures are common, and most can be managed by a period of immobilization. However, it remains challenging to identify those more complex fractures requiring the expertise of a hand surgeon to ensure a good outcome. The purpose of this study was to develop a prediction model for identification of complex pediatric hand fractures requiring care by a hand surgeon. METHODS: A 2-year retrospective cohort study of consecutively referred pediatric (<18 years) hand fracture patients was used to derive and internally validate a prediction model for identification of complex fractures requiring the expertise of a hand surgeon. These complex fractures were defined as those that required surgery, closed reduction, or four or more appointments with a hand surgeon. The model, derived by multivariable logistic regression analysis, was internally validated using bootstrapping and then translated into a risk index. RESULTS: Of 1170 fractures, 416 (35.6%) met criteria for a complex fracture. Multivariable regression analysis identified six significant predictors of complex fracture: open fracture, rotational deformity, angulation, condylar involvement, dislocation or subluxation, and displacement. Internal validation demonstrated good performance of the model (C-statistic = 0.88, calibration curve p = 0.935). A threshold of ≥1 point (ie, any one of the predictors) resulted in a simple, easy-to-use tool with 96.4% sensitivity and 45.5% specificity. CONCLUSIONS: A high-performing and clinically useful decision support tool was developed for emergency and urgent care physicians providing initial assessment for children with hand fractures. This tool will provide the basis for development of a clinical care pathway for pediatric hand fractures. Lippincott Williams & Wilkins 2021-04-20 /pmc/articles/PMC8057756/ /pubmed/33889473 http://dx.doi.org/10.1097/GOX.0000000000003543 Text en Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Hand/Peripheral Nerve
Hartley, Rebecca L.
Fraulin, Frankie O.G.
Harrop, A. Robertson
Faris, Peter
Wick, James
Ronksley, Paul E.
Derivation and Internal Validation of a Prediction Model for Pediatric Hand Fracture Triage
title Derivation and Internal Validation of a Prediction Model for Pediatric Hand Fracture Triage
title_full Derivation and Internal Validation of a Prediction Model for Pediatric Hand Fracture Triage
title_fullStr Derivation and Internal Validation of a Prediction Model for Pediatric Hand Fracture Triage
title_full_unstemmed Derivation and Internal Validation of a Prediction Model for Pediatric Hand Fracture Triage
title_short Derivation and Internal Validation of a Prediction Model for Pediatric Hand Fracture Triage
title_sort derivation and internal validation of a prediction model for pediatric hand fracture triage
topic Hand/Peripheral Nerve
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057756/
https://www.ncbi.nlm.nih.gov/pubmed/33889473
http://dx.doi.org/10.1097/GOX.0000000000003543
work_keys_str_mv AT hartleyrebeccal derivationandinternalvalidationofapredictionmodelforpediatrichandfracturetriage
AT fraulinfrankieog derivationandinternalvalidationofapredictionmodelforpediatrichandfracturetriage
AT harroparobertson derivationandinternalvalidationofapredictionmodelforpediatrichandfracturetriage
AT farispeter derivationandinternalvalidationofapredictionmodelforpediatrichandfracturetriage
AT wickjames derivationandinternalvalidationofapredictionmodelforpediatrichandfracturetriage
AT ronksleypaule derivationandinternalvalidationofapredictionmodelforpediatrichandfracturetriage