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Rosuvastatin Enhances Alveolar Fluid Clearance in Lipopolysaccharide-Induced Acute Lung Injury by Activating the Expression of Sodium Channel and Na,K-ATPase via the PI3K/AKT/Nedd4-2 Pathway

BACKGROUND: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are devastating clinical conditions characterized by pulmonary epithelial damage and protein-rich fluid accumulation in the alveolar spaces. Statins are a class of HMG-CoA reductase inhibitors, which exert cholesterol...

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Detalles Bibliográficos
Autores principales:	Xu, Hao-Ran, Yang, Qian, Xiang, Shu-Yang, Zhang, Pu-Hong, Ye, Yang, Chen, Yan, Xu, Ke-Wen, Ren, Xi-Ya, Mei, Hong-Xia, Shen, Chen-Xi, Ma, Hong-Yu, Smith, Fang-Gao, Jin, Sheng-Wei, Wang, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057837/ https://www.ncbi.nlm.nih.gov/pubmed/33889010 http://dx.doi.org/10.2147/JIR.S299267

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