Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound

Invasive liver abscess syndrome (ILAS) is caused by strains of hypervirulent Klebsiella pneumoniae (hvKp) and has emerged as the leading cause of liver abscesses in immuno-competent patients (L.K. Siu et al. Lancet Infect Dis 2012; 12: 881–87). ILAS is frequently associated with metastatic spread in...

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Autores principales: Bielow, Tobias, Blank, Valentin, Opitz, Sabine, Gößmann, Holger, Hecker, Martin, Seehofer, Daniel, Lübbert, Christoph, Karlas, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057861/
https://www.ncbi.nlm.nih.gov/pubmed/33889805
http://dx.doi.org/10.1055/a-1471-6907
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author Bielow, Tobias
Blank, Valentin
Opitz, Sabine
Gößmann, Holger
Hecker, Martin
Seehofer, Daniel
Lübbert, Christoph
Karlas, Thomas
author_facet Bielow, Tobias
Blank, Valentin
Opitz, Sabine
Gößmann, Holger
Hecker, Martin
Seehofer, Daniel
Lübbert, Christoph
Karlas, Thomas
author_sort Bielow, Tobias
collection PubMed
description Invasive liver abscess syndrome (ILAS) is caused by strains of hypervirulent Klebsiella pneumoniae (hvKp) and has emerged as the leading cause of liver abscesses in immuno-competent patients (L.K. Siu et al. Lancet Infect Dis 2012; 12: 881–87). ILAS is frequently associated with metastatic spread including the eyes, lungs, and the central nervous system. The morbidity and mortality of affected patients are increased compared to liver abscesses of other origin, especially in cases with concomitant diabetes mellitus (J. E. Choby et al. J Intern Med 2020; 287(3): 283–300). Immediate diagnosis and early intervention are essential for an optimal outcome. Therefore, ultrasound plays a crucial role if hvKp is suspected. However, experience with the characteristics of such abscesses on contrast-enhanced ultrasound (CEUS) is very limited.
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spelling pubmed-80578612021-04-21 Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound Bielow, Tobias Blank, Valentin Opitz, Sabine Gößmann, Holger Hecker, Martin Seehofer, Daniel Lübbert, Christoph Karlas, Thomas Ultrasound Int Open Invasive liver abscess syndrome (ILAS) is caused by strains of hypervirulent Klebsiella pneumoniae (hvKp) and has emerged as the leading cause of liver abscesses in immuno-competent patients (L.K. Siu et al. Lancet Infect Dis 2012; 12: 881–87). ILAS is frequently associated with metastatic spread including the eyes, lungs, and the central nervous system. The morbidity and mortality of affected patients are increased compared to liver abscesses of other origin, especially in cases with concomitant diabetes mellitus (J. E. Choby et al. J Intern Med 2020; 287(3): 283–300). Immediate diagnosis and early intervention are essential for an optimal outcome. Therefore, ultrasound plays a crucial role if hvKp is suspected. However, experience with the characteristics of such abscesses on contrast-enhanced ultrasound (CEUS) is very limited. Georg Thieme Verlag KG 2021-04 2021-04-20 /pmc/articles/PMC8057861/ /pubmed/33889805 http://dx.doi.org/10.1055/a-1471-6907 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Bielow, Tobias
Blank, Valentin
Opitz, Sabine
Gößmann, Holger
Hecker, Martin
Seehofer, Daniel
Lübbert, Christoph
Karlas, Thomas
Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound
title Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound
title_full Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound
title_fullStr Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound
title_full_unstemmed Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound
title_short Klebsiella Pneumoniae Liver Abscess Syndrome – A Challenge for Contrast-Enhanced Ultrasound
title_sort klebsiella pneumoniae liver abscess syndrome – a challenge for contrast-enhanced ultrasound
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057861/
https://www.ncbi.nlm.nih.gov/pubmed/33889805
http://dx.doi.org/10.1055/a-1471-6907
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