The impact of COVID-19 on the cell and gene therapies industry: Disruptions, opportunities, and future prospects

Coronavirus 2019 (COVID-19) has caused significant disruption to the cell and gene therapy (CGT) industry, which has historically faced substantial complexities in supply of materials, and manufacturing and logistics processes. As decision-makers shifted their priorities to COVID-19-related issues,...

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Autores principales: Qiu, Tingting, Wang, Yitong, Liang, Shuyao, Han, Ru, Toumi, Mondher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Keynote (Green)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057929/
https://www.ncbi.nlm.nih.gov/pubmed/33892148
http://dx.doi.org/10.1016/j.drudis.2021.04.020
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author Qiu, Tingting
Wang, Yitong
Liang, Shuyao
Han, Ru
Toumi, Mondher
author_facet Qiu, Tingting
Wang, Yitong
Liang, Shuyao
Han, Ru
Toumi, Mondher
author_sort Qiu, Tingting
collection PubMed
description Coronavirus 2019 (COVID-19) has caused significant disruption to the cell and gene therapy (CGT) industry, which has historically faced substantial complexities in supply of materials, and manufacturing and logistics processes. As decision-makers shifted their priorities to COVID-19-related issues, the challenges in market authorisation, and price and reimbursement of CGTs were amplified. Nevertheless, it is encouraging to see that some CGT developers are adapting their efforts toward the development of promising COVID-19-related therapeutics and vaccines. Manufacturing resilience, digitalisation, telemedicine, value-based pricing, and innovative payment mechanisms will be increasingly harnessed to ensure that market access of CGTs is not severely disrupted.
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spelling pubmed-80579292021-04-21 The impact of COVID-19 on the cell and gene therapies industry: Disruptions, opportunities, and future prospects Qiu, Tingting Wang, Yitong Liang, Shuyao Han, Ru Toumi, Mondher Drug Discov Today Keynote (Green) Coronavirus 2019 (COVID-19) has caused significant disruption to the cell and gene therapy (CGT) industry, which has historically faced substantial complexities in supply of materials, and manufacturing and logistics processes. As decision-makers shifted their priorities to COVID-19-related issues, the challenges in market authorisation, and price and reimbursement of CGTs were amplified. Nevertheless, it is encouraging to see that some CGT developers are adapting their efforts toward the development of promising COVID-19-related therapeutics and vaccines. Manufacturing resilience, digitalisation, telemedicine, value-based pricing, and innovative payment mechanisms will be increasingly harnessed to ensure that market access of CGTs is not severely disrupted. Elsevier Ltd. 2021-10 2021-04-21 /pmc/articles/PMC8057929/ /pubmed/33892148 http://dx.doi.org/10.1016/j.drudis.2021.04.020 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Keynote (Green)
Qiu, Tingting
Wang, Yitong
Liang, Shuyao
Han, Ru
Toumi, Mondher
The impact of COVID-19 on the cell and gene therapies industry: Disruptions, opportunities, and future prospects
title The impact of COVID-19 on the cell and gene therapies industry: Disruptions, opportunities, and future prospects
title_full The impact of COVID-19 on the cell and gene therapies industry: Disruptions, opportunities, and future prospects
title_fullStr The impact of COVID-19 on the cell and gene therapies industry: Disruptions, opportunities, and future prospects
title_full_unstemmed The impact of COVID-19 on the cell and gene therapies industry: Disruptions, opportunities, and future prospects
title_short The impact of COVID-19 on the cell and gene therapies industry: Disruptions, opportunities, and future prospects
title_sort impact of covid-19 on the cell and gene therapies industry: disruptions, opportunities, and future prospects
topic Keynote (Green)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057929/
https://www.ncbi.nlm.nih.gov/pubmed/33892148
http://dx.doi.org/10.1016/j.drudis.2021.04.020
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