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Long-term depression at hippocampal mossy fiber-CA3 synapses involves BDNF but is not mediated by p75NTR signaling

BDNF plays a crucial role in the regulation of synaptic plasticity. It is synthesized as a precursor (proBDNF) that can be proteolytically cleaved to mature BDNF (mBDNF). Previous studies revealed a bidirectional mode of BDNF actions, where long-term potentiation (LTP) was mediated by mBDNF through...

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Detalles Bibliográficos
Autores principales:	Garad, Machhindra, Edelmann, Elke, Leßmann, Volkmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058084/ https://www.ncbi.nlm.nih.gov/pubmed/33879805 http://dx.doi.org/10.1038/s41598-021-87769-9

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