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Oridonin-Loaded Nanoparticles Inhibit Breast Cancer Progression Through Regulation of ROS-Related Nrf2 Signaling Pathway

Oridonin (ORI) has been shown to inhibit tumor cell growth and proliferation in vitro, while its optimum anti-tumor activity in vivo is limited due to the poor aqueous solubility and bioavailability. In this study, to improve the bioavailability, we developed a nanoparticle-based drug delivery syste...

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Detalles Bibliográficos
Autores principales: Zhao, Yue, Xiao, Weiwei, Peng, Wanqing, Huang, Qinghua, Wu, Kunru, Evans, Colin E., Liu, Xinguang, Jin, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058419/
https://www.ncbi.nlm.nih.gov/pubmed/33898397
http://dx.doi.org/10.3389/fbioe.2021.600579