Cargando…

Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients

INTRODUCTION: Emerging evidence has suggested that inherited factors are also involved in lung cancer development. However, most studies focused on well-elucidated cancer predisposition genes, the majority of which are tumor suppressor genes. The profile of germline mutations in oncogenic driver gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Jie, Li, Hefei, Li, Ben, Li, Wei, Guo, Qiang, Hu, Ling, Song, Zizheng, Zhou, Bin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058453/ https://www.ncbi.nlm.nih.gov/pubmed/33898318 http://dx.doi.org/10.3389/fonc.2021.647598

Ejemplares similares

Mutation spectrum of germline cancer susceptibility genes among unselected Chinese colorectal cancer patients
por: Gong, Rui, et al.
Publicado: (2019)

Comparison of BRCA versus non-BRCA germline mutations and associated somatic mutation profiles in patients with unselected breast cancer
por: Chen, Bo, et al.
Publicado: (2020)

Germline Mutational Landscape in Chinese Patients With Advanced Breast Cancer
por: Zhang, Jiayang, et al.
Publicado: (2022)

A Germline Mutation in ATR Is Associated With Lung Adenocarcinoma in Asian Patients
por: Bao, Guangyao, et al.
Publicado: (2022)

Analysis of BRCA Germline Mutations in Chinese Prostate Cancer Patients
por: Chen, Wei, et al.
Publicado: (2022)

Germline and Somatic BRCA1/2 Mutations in 172 Chinese Women With Epithelial Ovarian Cancer
por: You, Yan, et al.
Publicado: (2020)

Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer
por: Yu, Haipeng, et al.
Publicado: (2022)

Comprehensive germline-genomic and clinical profiling in 160 unselected children and adolescents with cancer
por: Wagener, Rabea, et al.
Publicado: (2021)

Germline MUTYH gene mutations are not frequently found in unselected patients with papillary breast carcinoma
por: Boesaard, Ewout P, et al.
Publicado: (2014)

The Value of Radiotherapy for Advanced Non-Small Cell Lung Cancer With Oncogene Driver-Mutation
por: Cui, Jinfeng, et al.
Publicado: (2022)

Germline Mutation Landscape and Associated Clinical Characteristics in Chinese Patients With Renal Cell Carcinoma
por: Kong, Wen, et al.
Publicado: (2021)

Germline pathogenic variants in unselected Korean men with prostate cancer
por: So, Min-Kyung, et al.
Publicado: (2022)

Prevalence and Landscape of Pathogenic or Likely Pathogenic Germline Variants and Their Association With Somatic Phenotype in Unselected Chinese Patients With Gynecologic Cancers
por: Wen, Hao, et al.
Publicado: (2023)

Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study
por: Lin, Xinqing, et al.
Publicado: (2021)

Case Report: Lung adenocarcinoma associated with germline ERCC2 frameshift mutation
por: Liu, Lili, et al.
Publicado: (2023)

Choroid Plexus Carcinomas With TP53 Germline Mutations: Management and Outcome
por: Li, Yanong, et al.
Publicado: (2021)

Clinical and genomic features of Chinese lung cancer patients with germline mutations
por: Peng, Wenying, et al.
Publicado: (2022)

Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations
por: Jiang, Jingrui, et al.
Publicado: (2018)

Concurrent Oncogene Mutation Profile in Chinese Patients With Stage Ib Lung Adenocarcinoma
por: Wen, Ying-Sheng, et al.
Publicado: (2014)

Somatic and germline aberrations in homologous recombination repair genes in Chinese prostate cancer patients
por: Liu, Yixiao, et al.
Publicado: (2023)

Concomitant Pathogenic Mutations and Fusions of Driver Oncogenes in Tumors
por: Zhang, Runjiao, et al.
Publicado: (2021)

Identification of Germline Mutations in Upper Tract Urothelial Carcinoma With Suspected Lynch Syndrome
por: Guan, Bao, et al.
Publicado: (2022)

Germline Profiling and Molecular Characterization of Early Onset Metastatic Colorectal Cancer
por: Xu, Ting, et al.
Publicado: (2020)

RFWD2 Knockdown as a Blocker to Reverse the Oncogenic Role of TRIB2 in Lung Adenocarcinoma
por: Hao, Ruimin, et al.
Publicado: (2021)

Clinical Significance of Germline Cancer Predisposing Variants in Unselected Patients with Pancreatic Adenocarcinoma
por: Fountzilas, Elena, et al.
Publicado: (2021)

Case Report: Coinheritance of Germline Mutations in APC and BRCA1 in Colorectal Cancer
por: Huang, Wei, et al.
Publicado: (2021)

Germline Mutations in Patients With Early-Onset Prostate Cancer
por: Tang, Tang, et al.
Publicado: (2022)

Catalog of Lung Cancer Gene Mutations Among Chinese Patients
por: Xue, Xinying, et al.
Publicado: (2020)

Genetic Alteration Profiling of Chinese Lung Adenocarcinoma and Its Effect on Targeted Therapy Efficacy
por: Liu, Jie, et al.
Publicado: (2021)

Comprehensive Study of Germline Mutations and Double-Hit Events in Esophageal Squamous Cell Cancer
por: Zeng, Bing, et al.
Publicado: (2021)

Integrated driver mutations profile of chinese gastrointestinal-natural killer/T-cell lymphoma
por: Li, Shanshan, et al.
Publicado: (2022)

The Effect of the Kirsten Rat Sarcoma Viral Oncogene Homolog (Kras) Proto-Oncogene, GTPase Genetic Polymorphism on the Safety and Efficacy of Bevacizumab Combination Treatment Regimens for Patients with Nonsquamous, Non-Small Cell Lung Cancer with Brain Metastases
por: Song, Zizheng, et al.
Publicado: (2022)

Overview on population screening for carriers with germline BRCA mutation in China
por: Lei, Huijun, et al.
Publicado: (2022)

Survival Benefit and Genetic Profile of Pemetrexed as Initial Chemotherapy in Selected Chinese Patients With Advanced Lung Adenocarcinoma
por: Guo, Long-Hua, et al.
Publicado: (2020)

Frequency and Clinical Characteristics of Unselected Korean Gastric Cancer Patients with a Germline CDH1 V832M Mutation
por: Shin, Saeam, et al.
Publicado: (2020)

Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients
por: Wang, Rui, et al.
Publicado: (2015)

MYC/MAX-Activated LINC00958 Promotes Lung Adenocarcinoma by Oncogenic Transcriptional Reprogramming Through HOXA1 Activation
por: Zhang, Tao, et al.
Publicado: (2022)

Germline Counterparts of Oncogenic Mutations: Who Gives a JAK?
por: Mead, Adam J., et al.
Publicado: (2013)

A Lung Cancer Patient Harboring a Rare Oncogenic EGFR Exon 20 V786M Mutation Responded to a Third-Generation Tyrosine Kinase Inhibitor: Case Report and Review of the Literature
por: Zhu, Qi, et al.
Publicado: (2022)

Case Report: Co-Existence of BRCA2 and PALB2 Germline Mutations in Familial Prostate Cancer With Solitary Lung Metastasis
por: Tang, Tang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_j8dtut1pphgl43f00619iekbo7