Cancer-secreted exosomal miR-1468-5p promotes tumor immune escape via the immunosuppressive reprogramming of lymphatic vessels

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Cancer-associated lymphatic endothelial cells (LECs) are an active barrier to the effector arm of the anti-tumor immune response; however, it remains unclear how LECs become immunosuppressive in the tumor microenvironment (TME). Exosomal microRNAs (miRNAs) have recently been implicated in intercellu...

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Detalles Bibliográficos
Autores principales: Zhou, Chenfei, Wei, Wenfei, Ma, Jing, Yang, Yang, Liang, Luojiao, Zhang, Yanmei, Wang, Zici, Chen, Xiaojing, Huang, Lei, Wang, Wei, Wu, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058488/
https://www.ncbi.nlm.nih.gov/pubmed/33388421
http://dx.doi.org/10.1016/j.ymthe.2020.12.034
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