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Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection

Objectives: Several factors determining differences between types A and B aortic dissection (AD) have been reported; however, little data exist examining their differences in left ventricular hypertrophy (LVH). We compared the prevalence of LVH in patients with types A and B AD. Methods: We retrospe...

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Autores principales: Akutsu, Koichi, Ozaki, Kensuke, Oshima, Susumu, Sakurai, Shigeru, Ohara, Takahiro, Otsuka, Toshiaki, Yamamoto, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058545/
https://www.ncbi.nlm.nih.gov/pubmed/33148929
http://dx.doi.org/10.5761/atcs.oa.20-00137
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author Akutsu, Koichi
Ozaki, Kensuke
Oshima, Susumu
Sakurai, Shigeru
Ohara, Takahiro
Otsuka, Toshiaki
Yamamoto, Shin
author_facet Akutsu, Koichi
Ozaki, Kensuke
Oshima, Susumu
Sakurai, Shigeru
Ohara, Takahiro
Otsuka, Toshiaki
Yamamoto, Shin
author_sort Akutsu, Koichi
collection PubMed
description Objectives: Several factors determining differences between types A and B aortic dissection (AD) have been reported; however, little data exist examining their differences in left ventricular hypertrophy (LVH). We compared the prevalence of LVH in patients with types A and B AD. Methods: We retrospectively analyzed 334 patients with acute AD (227 type A; 107 type B). Concentric hypertrophy (CH; increased left ventricular mass index [LVMI] and relative wall thickness [RWT]) is one of four types of left ventricular (LV) geometry thought to be most associated with hypertension. We compared LVMI and the prevalence of CH in patients with types A or B AD. Multivariate logistic regression analyses of variables associated with type B AD were performed. Results: Comparing type A and B AD, LVMI (95 ± 26 vs.107 ± 28, p <0.001) and prevalence of CH (26% vs. 44%, p = 0.001) were higher in type B AD. In multivariate analysis, CH was an independent factor associated with type B AD (odds ratio: 2.62, confidence interval: 1.54–4.47, p <0.001). Conclusions: Our data suggested LVH was more prevalent in type B than in type A AD. Considering LVH usually results from hypertension, patients with type B AD may be more affected by hypertension than those with type A.
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spelling pubmed-80585452021-07-06 Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection Akutsu, Koichi Ozaki, Kensuke Oshima, Susumu Sakurai, Shigeru Ohara, Takahiro Otsuka, Toshiaki Yamamoto, Shin Ann Thorac Cardiovasc Surg Original Article Objectives: Several factors determining differences between types A and B aortic dissection (AD) have been reported; however, little data exist examining their differences in left ventricular hypertrophy (LVH). We compared the prevalence of LVH in patients with types A and B AD. Methods: We retrospectively analyzed 334 patients with acute AD (227 type A; 107 type B). Concentric hypertrophy (CH; increased left ventricular mass index [LVMI] and relative wall thickness [RWT]) is one of four types of left ventricular (LV) geometry thought to be most associated with hypertension. We compared LVMI and the prevalence of CH in patients with types A or B AD. Multivariate logistic regression analyses of variables associated with type B AD were performed. Results: Comparing type A and B AD, LVMI (95 ± 26 vs.107 ± 28, p <0.001) and prevalence of CH (26% vs. 44%, p = 0.001) were higher in type B AD. In multivariate analysis, CH was an independent factor associated with type B AD (odds ratio: 2.62, confidence interval: 1.54–4.47, p <0.001). Conclusions: Our data suggested LVH was more prevalent in type B than in type A AD. Considering LVH usually results from hypertension, patients with type B AD may be more affected by hypertension than those with type A. The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2020-11-03 2021 /pmc/articles/PMC8058545/ /pubmed/33148929 http://dx.doi.org/10.5761/atcs.oa.20-00137 Text en ©2021 Annals of Thoracic and Cardiovascular Surgery https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NonDerivatives International License (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Article
Akutsu, Koichi
Ozaki, Kensuke
Oshima, Susumu
Sakurai, Shigeru
Ohara, Takahiro
Otsuka, Toshiaki
Yamamoto, Shin
Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection
title Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection
title_full Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection
title_fullStr Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection
title_full_unstemmed Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection
title_short Left Ventricular Hypertrophy Is More Prevalent in Type B than Type A Aortic Dissection
title_sort left ventricular hypertrophy is more prevalent in type b than type a aortic dissection
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058545/
https://www.ncbi.nlm.nih.gov/pubmed/33148929
http://dx.doi.org/10.5761/atcs.oa.20-00137
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