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Activity-dependent conformational transitions of the insulin receptor–related receptor
The insulin receptor (IR), insulin-like growth factor 1 receptor (IGF-1R), and insulin receptor-related receptor (IRR) form a mini family of predimerized receptor-like tyrosine kinases. IR and IGF-1R bind to their peptide agonists triggering metabolic and cell growth responses. In contrast, IRR, des...
Autores principales: | Batishchev, Oleg V., Kuzmina, Natalia V., Mozhaev, Andrey A., Goryashchenko, Alexander S., Mileshina, Ekaterina D., Orsa, Alexander N., Bocharov, Eduard V., Deyev, Igor E., Petrenko, Alexander G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058561/ https://www.ncbi.nlm.nih.gov/pubmed/33713705 http://dx.doi.org/10.1016/j.jbc.2021.100534 |
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