Expression of SARS coronavirus 1 spike protein from a herpesviral vector induces innate immune signaling and neutralizing antibody responses

SARS coronavirus 1 (SARS-CoV-1) causes a respiratory infection that can lead to acute respiratory distress characterized by inflammation and high levels of cytokines in the lung tissue. In this study we constructed a herpes simplex virus 1 replication-defective mutant vector expressing SARS-CoV-1 sp...

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Detalles Bibliográficos
Autores principales: Kurt-Jones, Evelyn A., Dudek, Timothy E., Watanabe, Daisuke, Mandell, Leisa, Che, Jenny, Zhou, Shenghua, Cao, LuCheng, Greenough, Thomas, Babcock, Gregory J., Diaz, Fernando, Oh, Hyung Suk, Zhou, Changhong, Finberg, Robert W., Knipe, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058630/
https://www.ncbi.nlm.nih.gov/pubmed/33930819
http://dx.doi.org/10.1016/j.virol.2021.04.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058630/
https://www.ncbi.nlm.nih.gov/pubmed/33930819
http://dx.doi.org/10.1016/j.virol.2021.04.006

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