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Expression of SARS coronavirus 1 spike protein from a herpesviral vector induces innate immune signaling and neutralizing antibody responses
SARS coronavirus 1 (SARS-CoV-1) causes a respiratory infection that can lead to acute respiratory distress characterized by inflammation and high levels of cytokines in the lung tissue. In this study we constructed a herpes simplex virus 1 replication-defective mutant vector expressing SARS-CoV-1 sp...
Autores principales: | Kurt-Jones, Evelyn A., Dudek, Timothy E., Watanabe, Daisuke, Mandell, Leisa, Che, Jenny, Zhou, Shenghua, Cao, LuCheng, Greenough, Thomas, Babcock, Gregory J., Diaz, Fernando, Oh, Hyung Suk, Zhou, Changhong, Finberg, Robert W., Knipe, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058630/ https://www.ncbi.nlm.nih.gov/pubmed/33930819 http://dx.doi.org/10.1016/j.virol.2021.04.006 |
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