Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy

Endoscopic removal of large (≥ 20 mm) non-pedunculated colorectal lesions (LNPCLs) may result in major adverse events, such as delayed bleeding (DB) and delayed perforation (DP), despite closure of the mucosal defects with clips. Topical application of a coverage agent refers to the creation of a sh...

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Autores principales: Lorenzo-Zúñiga, Vicente, Bustamante-Balén, Marco, Pons-Beltrán, Vicente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058649/
https://www.ncbi.nlm.nih.gov/pubmed/33958843
http://dx.doi.org/10.3748/wjg.v27.i15.1563
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author Lorenzo-Zúñiga, Vicente
Bustamante-Balén, Marco
Pons-Beltrán, Vicente
author_facet Lorenzo-Zúñiga, Vicente
Bustamante-Balén, Marco
Pons-Beltrán, Vicente
author_sort Lorenzo-Zúñiga, Vicente
collection PubMed
description Endoscopic removal of large (≥ 20 mm) non-pedunculated colorectal lesions (LNPCLs) may result in major adverse events, such as delayed bleeding (DB) and delayed perforation (DP), despite closure of the mucosal defects with clips. Topical application of a coverage agent refers to the creation of a shield with a biocompatible medical device (tissue or hydrogel) with proven bioactive properties. Coverage of the eschar after endoscopic resection provides shielding protection to prevent delayed complications. The aim of the present review was to systematically collect and review the currently available literature regarding the prevention of DB and DP with coverage agents after endoscopic mucosal resection or endoscopic submucosal dissection of LNPCLs.
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spelling pubmed-80586492021-05-05 Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy Lorenzo-Zúñiga, Vicente Bustamante-Balén, Marco Pons-Beltrán, Vicente World J Gastroenterol Minireviews Endoscopic removal of large (≥ 20 mm) non-pedunculated colorectal lesions (LNPCLs) may result in major adverse events, such as delayed bleeding (DB) and delayed perforation (DP), despite closure of the mucosal defects with clips. Topical application of a coverage agent refers to the creation of a shield with a biocompatible medical device (tissue or hydrogel) with proven bioactive properties. Coverage of the eschar after endoscopic resection provides shielding protection to prevent delayed complications. The aim of the present review was to systematically collect and review the currently available literature regarding the prevention of DB and DP with coverage agents after endoscopic mucosal resection or endoscopic submucosal dissection of LNPCLs. Baishideng Publishing Group Inc 2021-04-21 2021-04-21 /pmc/articles/PMC8058649/ /pubmed/33958843 http://dx.doi.org/10.3748/wjg.v27.i15.1563 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Minireviews
Lorenzo-Zúñiga, Vicente
Bustamante-Balén, Marco
Pons-Beltrán, Vicente
Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy
title Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy
title_full Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy
title_fullStr Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy
title_full_unstemmed Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy
title_short Prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: Current landscape in gastrointestinal endoscopy
title_sort prevention of late complications with coverage agents in endoscopic resection of colorectal lesions: current landscape in gastrointestinal endoscopy
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058649/
https://www.ncbi.nlm.nih.gov/pubmed/33958843
http://dx.doi.org/10.3748/wjg.v27.i15.1563
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