Cargando…
Engineering protein theranostics using bio-orthogonal asparaginyl peptide ligases
Background: Protein theranostics integrate both diagnostic and treatment functions on a single disease-targeting protein. However, the preparation of these multimodal agents remains a major challenge. Ideally, conventional recombinant proteins should be used as starting materials for modification wi...
Autores principales: | Wang, Zhen, Zhang, Dingpeng, Hemu, Xinya, Hu, Side, To, Janet, Zhang, Xiaohong, Lescar, Julien, Tam, James P., Liu, Chuan-Fa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058723/ https://www.ncbi.nlm.nih.gov/pubmed/33897886 http://dx.doi.org/10.7150/thno.53615 |
Ejemplares similares
-
Consensus design and engineering of an efficient and high-yield peptide asparaginyl ligase for protein cyclization and ligation
por: Hemu, Xinya, et al.
Publicado: (2023) -
Vypal2: A Versatile Peptide Ligase for Precision Tailoring of Proteins
por: Zhang, Dingpeng, et al.
Publicado: (2021) -
On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation
por: Chua, Niying, et al.
Publicado: (2023) -
Site-Specific Protein Modifications by an Engineered Asparaginyl Endopeptidase from Viola canadensis
por: Chen, Yu, et al.
Publicado: (2021) -
Macrocyclic Antimicrobial Peptides Engineered from ω-Conotoxin
por: Hemu, Xinya, et al.
Publicado: (2017)