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Female mice lacking ERβ display excitatory/inhibitory synaptic imbalance to drive the pathogenesis of temporal lobe epilepsy

Epilepsy is a highly prevalent and drug-refractory neurological disorder characterized by spontaneous recurrent seizures. Estrogen is identified to be proconvulsant and lowers the seizure threshold of female epilepsy. Estrogen receptor β (ERβ) has been proposed to mediate neuroprotection in epilepsy...

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Detalles Bibliográficos
Autores principales: Wang, Zhongke, Xie, Ruxin, Yang, Xiaolin, Yin, Huachun, Li, Xin, Liu, Tianyao, Ma, Yuanyuan, Gao, Junwei, Zang, Zhenle, Ruan, Ruotong, Li, Yang, Huang, Kaixuan, Chen, Qingbo, Shen, Kaifeng, Lv, Shengqing, Zhang, Chunqing, Yang, Hui, Warner, Maragret, Gustafsson, Jan-Ake, Liu, Shiyong, Fan, Xiaotang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8058727/
https://www.ncbi.nlm.nih.gov/pubmed/33897900
http://dx.doi.org/10.7150/thno.56331